Hi, thanks for your response, this is now resolved.
I downloaded that and it let me view the logs but wasn't much help because there was so much going on due to the issues.
Server Manager also wouldn't open and I came across this
As a couple of the solutions suggest, what worked for me was copying the machine.config file from
C:\Windows\Microsoft.NET\Framework\v4.0.30319\Config
to
C:\Windows\Microsoft.NET\Framework64\v4.0.30319\Config
I checked on a couple of other servers I have and the files were identical in both locations (servers without these issues obviously have the file in both locations, mine was missing in the Framework64 location on the problem server).
Reboot and hey presto, everything working again. I guess that file was somehow damaged when I uninstalled the Jan 2022 cumulative update due to the issues with that update.
Thanks for your help.
Just to add, yes the entire server is backed up by an agentless vm backup software. Veeam is just an additional file level backup I run within the server for an extra backup copy for the main file server volume. Interestingly, the Veeam backups appear to have still taken place each day, despite the one and only Veeam service having not been running for many days, and no scheduled tasks.. not sure how that works.
