I've been contemplating Google Chrome or IE9 for a while for a speedier browsing experience compared to Firefox, but with the addition of tab grouping and Adblock Plus' current focus on Firefox, I'm pretty much locked in with FF right now. I have well over 600 tabs at a time on Firefox, which just is impossible to handle properly with IE9 or Chrome. Also certain plugins like Lazarus have been a lifesaver for me, and have forced my hand to retain its grip on Firefox. Granted, I despise the new versioning system they have going now, but fortunately their ESR version of FF has greatly relieved my stress from it.
Firefox is a slow beast, but it is a beast nonetheless.