I used to be a long-time user of Opera, but I started having issues with crashing. They're a much smaller team, and can't patch as quickly as Mozilla or Google. This might have changed now, but Chrome and FF had overtaken Opera in terms of security and sand-boxing when I switched to Chrome.
Been using Chrome for the last year or so - very fast. I've tried IE10, but it just doesn't compare speed or feature wise. It's a huge improvement over previous IE versions, but I only ever use it for compatibility checking/maintenance stuff on Sysnative + various websites. It's useful to have a browser where I'm not logged into anything, without any plugins, just to see what sites look like for everyone else.
I would be tempted to try FF again, might switch over again soon. I used FF 1.5 and 2 for a long time, before switching over to Opera.
