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Good point!!, I'll need to ask another member of the team to check the portal as I don't have access they have probably left for the day now so will ask tomorrowGreat, please check also that Microsoft's installer (*.exe) of KB4052623 is not blocked by Trend Micro even it's signed.
Post is 9 pages deep and I still feel this is never going to get solved.
reg save "HKLM\SOFTWARE\Policies\Microsoft\Windows Defender" "%userprofile%\Desktop\policies.hiv"
reg delete "HKLM\SOFTWARE\Policies\Microsoft\Windows Defender" /v DisableAntiSpyware /f
[StandardOutput]: CmdTool: Failed with hr = 0x8007041D. Check C:\Users\we02dc\AppData\Local\Temp\MpCmdRun.log for more information
2. So I've installed KB4052623 from this link https://catalog.s.download.windowsu..._d3d9fb1c3b6d1c3c90555e3acc9f630bc812c8fe.exe
3. This update created the DIR: C:\ProgramData\Microsoft\Windows Defender\Platform\4.18.24050.7-1