Re-booting with the anti-virus software disabled did not fix the issue. Our A/V software in our vSphere environment is agentless, so there really isn't a way to un-install it. There were four other security updates that got installed on my most recent attempt at windows updates. This is really perplexing. I have never experienced an issue like this in over 20 years of working on windows/computers. I am starting to think about just waiting for the May cumulative update to see if that works. And if that should fail I am thinking about creating a brand new OS layer for the VDI environment, although that is quite the task and requires re-creating all of our application layers also.